Over the last month information has been coming through about Phase 1 clinical trails in HDAC inhibitors for Friedreich’s Ataxia. In this Italian newspaper, it talks about the imminent start of a six months duration trial, only for adults, they do not say which drug, but as they say that “awakens the dormant gene”, I understand they are speaking about the HDAC inhibitors.
The patient organisation, goFAR released this information in French
http://www.babelfamily.org/fr/dernieres-nouvelles/296-ataxie-de-friedreich-de-bonnes-nouvelles-en-provenance-du-monde-de-la-recherche about the Italian clinical trial.
More recently Dr Richard Festenstein, Imperial College London has indicated that he is also starting a clinical trial using a HDAC inhibitor see the article below.